Cognitive
Caffeine facilitates performance in tasks involving working memory to a limited extent, but hinders performance in tasks that heavily depend on working memory, and caffeine appears to rather improve memory performance under suboptimal alertness conditions.
Most studies, however, found improvements in reaction time.
Caffeine acts as a central stimulant and enhances cognitive and psychomotor functioning, particularly during mental and physical fatigue, through effects that enhance alertness and vigilance.
Caffeine activates noradrenaline neurone and seems to affect the local release of dopamine,
The methylxanthine induces dose-response increases in locomotor activity in animals.
Nootropics
Nonprescription substances that can enhance brain performance or focus — such as caffeine and creatine — are also considered nootropics. They do not treat diseases but may have some effects on thinking, memory, or other mental functions.